Isotopically Labeled Compounds
Medchemexpress LLC Isonicotinamide-d4 | 1219799-40-2 | 99.91% | 126.15 | 25 MG
Isonicotinamide-d4 is a deuterium-labeled form of Isonicotinamide. It is commonly used as a tracer and an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS. Incorporating stable heavy isotopes into drug molecules aids in quantitation during drug development, and deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Deuterium-labeled for enhanced stability and tracking
- Can affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Resolvin D2-d5 | 1881277-33-3 | 99.0% | 10 UG
Resolvin D2-d5 is a deuterium-labeled internal standard of Resolvin D2 used as a tracer and quantitative internal standard for NMR, GC-MS, and LC-MS analyses. Supplied as a 10 μg solution in ethanol with high isotopic and chemical purity, it is intended for analytical quantification and tracer studies.
- Deuterium-labeled tracer for accurate mass spectrometric quantification.
- Supplied as a ready-to-use solution to simplify sample preparation.
- High chemical and isotopic purity for reliable analytical results.
- Suitable for NMR, GC-MS, and LC-MS as an internal standard.
- Stable when stored at -20°C for up to two years.
Medchemexpress LLC Tetrabenazine-d6 | 1392826-25-3 | ≥99.0% | 25 MG
Tetrabenazine-d6 (Deutetrabenazine) is a deuterium-labeled Tetrabenazine, the first deuterium approved worldwide for the research of Huntington's disease or other hyperkinetic movement disorders.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Extends the half-life in vivo.
- Improves oral bioavailability.
- Improves metabolic characteristics, potentially reducing toxic or reactive metabolites.
- Improves drug safety by reducing or eliminating adverse side effects.
- Preserves therapeutic properties, retaining similar biochemical potency and selectivity to hydrogen analogs.
Medchemexpress LLC Losartan-d4 | 1030937-27-9 | 99.9% | 426.94 | 1 MG
Losartan-d4 is the deuterium-labeled Losartan, an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Metoprolol-d5 | 959786-79-9 | 96.9% | 272.39 | 1 MG
Metoprolol-d5 is the deuterium labeled Metoprolol, an orally active, selective β1-adrenoceptor antagonist. It exhibits anti-inflammation, antitumor, and anti-angiogenic properties. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during drug development, with deuteration specifically impacting pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC ZLN005-d4 | 2410443-42-2 | 99.5% | 254.36 | 1 MG
ZLN005-d4 is a deuterium-labeled version of ZLN005. ZLN005 is a potent activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α).
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS
- Stable heavy isotopes, like deuterium, are incorporated into drug molecules and are used as tracers for quantitation during drug development
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC 2-Phenylglycine-d5 (DL-α-Phenylglycine-d5) | 358731-96-1 | 99.0% | 156.19 | 5 MG
2-Phenylglycine-d5 is the deuterium labeled 2-Phenylglycine. It is intended for research use only. This compound is a metabolite found in breast milk during the W2 to W4 lactation period. Deuteration has gained attention for its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled 2-Phenylglycine
- Metabolite found in breast milk during the W2 to W4 lactation period
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories D-SORBITOL (U-13C6, 98%+).25GR
D-SORBITOL | 0.25gr | 98%+ | 121067-66-1 | 188.13
eMolecules 70849-30-8 | Medchem Express | D-Galactose-13C | 25mg | 778475886 | HY-N0210S | 181.148 | C6H12O6
Medchem Express | D-Galactose-13C | 25mg | 778475886 | HY-N0210S | 70849-30-8 | 181.148 | C6H12O6
Cambridge Isotope Laboratories Deuterium Oxide (D, 99.9%) | 7789-20-0 | 10 x 0.7ml
Deuterium Oxide (D, 99.9%) | 7789-20-0 | 4 x 0.7ml
Cambridge Isotope Laboratories Methanol-D4 +0.03% V/V TMS | 811-98-3 | MFCD00044637 | 10 x 0.6 mL
Methanol-D4 +0.03% V/V TMS | Purity: 99.5% | Mol Wt: 36.07 | 811-98-3 | MFCD00044637 | 10 x 0.6 mL
Medchemexpress LLC Palmitoleic acid-13C16 | 2483735-57-3 | 99.20% | 270.29 | 1 MG
Palmitoleic acid-13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Asoxime-d4 dichlorid 500ug | 500UG
Asoxime-d4 (dichloride) is the deuterium labeled Asoxime dichloride Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor 7 nAChR Asoxime dichloride involves in modulating immunity response Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system[1